Cathedral Hill is a small area in the Western Addition neighborhood surrounding Saint Mary’s Cathedral on Geary Boulevard near Gough Street. The Roman Catholic Archdiocese of San Francisco and Sacred Heart Cathedral Preparatory are located in Cathedral Hill.

The Cathedral Hill Hotel, a historic building previously named the Jack Tar Hotel, was closed on October 30, 2009 and is being demolished in 2014 to make room for an expansion of the California Pacific Medical Center.